Welcome to the Scheff Lab!

“The goal of our research is to investigate whether therapy targeted to peripheral neurons in the cancer microenvironment can alleviate pain and slow carcinogenesis.”

Lab News

Dr. Scheff selected as 2021 Rita Allen Award in Pain Scholar

December 17th 2021

Dr. Scheff was selected as the 2021 Rita Allen Award in Pain Scholar. The lab will receive will receive funding for three years for the project entitled “CGRP: The link between cancer pain and progression in oral squamous cell carcinoma.”

Dr. Scheff receives 2021 HCC Junior Scholar Award

October 8th 2021

Dr. Scheff was selected as the recipient of the 2021 Hillman Cancer Center Junior Scholar Award in Population Science Cancer Research.

Dr. Nicole Scheff Awarded R01

June 1st 2021

Dr. Nicole Scheff has been awarded 5 years of funding by the National Institute of Health/National Institute of Dental and Craniofacial Research (NIH/NIDCR) for her grant, “Sympathetic modulation of head and neck cancer pain”.

What’s happening in the lab?

We are investigating how the peripheral nervous system responds and adapts to promote oral carcinogenesis. Click the image to learn more!

Newest publications

Sensory Neurotransmitter Calcitonin Gene-Related Peptide Modulates Tumor Growth and Lymphocyte Infiltration in Oral Squamous Cell Carcinoma

Oral cancer induced TRPV1 sensitization is mediated by PAR 2 signaling in primary afferent neurons innervating the cancer microenvironment

Neuroimmunology of cancer and associated symptomology.